Ubolt won't work on a forward bulkhead.
I suggested to Jerry to try Rocksett, since it is used on gas blocks on AR-15 barrels. It gets heat shock and vibe there, and lasts. So it might be good here as well. Just note it isn't intended for gap filling like one might use epoxy! The eyebolt would need to be screwed down solidly.
Alternative suggestion - put a strap through the eye of the bolt, anchored down with two small bolts on the bulkhead. So if it comes loose, it can't rotate. Consider it a variation of wiring the bolt.
I don't think you want to drill these bolts. They are fairly tough - or you shouldn't be using it (you are using a forged bolt, right?). You'd need a carbide bit and a drillpress. Then the hole would have a weak spot.
The purpose of the hole is to put a wire through and prevent rotation. But normally that is done through the head of a bolt, which should not be under much load. Every part of an eyebolt is under load. Adding a hole is not a great idea. Also note, it already has a hole, just larger... You can use that to wire it - wire or strap like I suggested above.
Gerald
PS - Forgot to add - Given the large difference in the coefficient of thermal expansion between steel and aluminum, Rocksett might not work. I've not tested it for this application. Usually it is used with steel and steel, or steel and titanium.
https://www.engineeringtoolbox.com/linear-expansion-coefficients-d_95.html