I usually weigh all the parts before building and override all the components when I create an initial, "dry" sim (without glue).
Then, as I build, I weigh again after each step and override the mass of the rocket and the CG. So I can see how each step - glue, primer, sanding primer off, paint - affect the possible flight of the rocket. It also helps me monitor my building, and I'm sometimes surprised how much or how little weight each step adds. The idea is that this might help me keep from overbuilding too much. Also, I just find the information interesting.
Once I am finished, I have a sim that reflects the real mass and CG of the model, and I know how each step changed it.