what are you running for spyware scanning software?
I have found that its a good idea to run a couple different ones - I use Ad-Aware (
www.lavasoft.de) and Spybot Search & Destroy (
www.safer-networking.org)
What one misses the other catches. Using these in combination is much more effective than either one by itself.
Also, be sure you have the latest updates to the spyware defintion list for both programs.
Spyware is a huge problem, most of it is benign but there a quite a few out there that break things. Some by intent, some because of faulty codiing.
If you are running XP you might try a system restore if you have a restore point.
I have had PCs in my shop that were completely useless because of Spyware - had on elast week with over 400 instances,
Some will not remove, they will initially look like they are gone but when you reboot they reload themselves from a hidden file somewhere disguised as a system file. In those case I usually google the name of the offending spyware and find a manual removal method.