Contact with the leaves or twigs causes the hollow,
silica-tipped hairs to break off and penetrate the skin and inject the toxins.
[10] The hairs cause an extremely painful stinging sensation that could last from several hours to 1–2 days, recurring to a lessening degree for several months or more whenever the area is touched, exposed to water, or subjected to temperature change. The injured area becomes covered with small, red spots joining together to form a red, swollen welt. The hairs are also believed to be released to the air when the plant is cut or cleared in large areas. Workers without respiratory protection have reported sneezing, runny noses, mild nasal bleeding and throat irritation while cutting or clearing. Ernie Rider, who was slapped in the face and torso with the foliage in 1963, said:
For two or three days the pain was almost unbearable; I couldn’t work or sleep, then it was pretty bad pain for another fortnight or so. The stinging persisted for two years and recurred every time I had a cold shower. ... There's nothing to rival it; it's ten times worse than anything else.