For using the art and hobby style airbrushes I have experience with, air pressure will need to be adjusted way down; in the 12 to 25 psi range, For automotive and industrial spray guns and airbrushes someone else will have to answer.
Top feed versus bottom feed is a yes, it is both application and preference. In general, with the hobby and art style airbrushes, top feed have been used for finer detail work while bottom feed which often has more paint capacity was used for overall work.
That large tank will be nice. One thing you don't want is moisture coming through with the air. I'm pretty sure the large tank will help there; and there are in-line moisture traps available from at least one airbrush maker to put in the air line to the brush. (gosh, mine is what, thirty years old?)
Oh, that's another thing, a well cared for quality air brush will last at least half of forever. There may be a seal or bushing need to be replaced from normal usage wear, but the good airbrushes are made to last.
And you know that old saying, "cleanliness is next to godliness"? Totally true for airbrush innards. You want to clean the inside with near-religious fervor after using acrylic paints.
Build up and blockages can come quickly. And acrylics are not like oils and enamels which can be re-softened with solvent.
However, in the model train hobby there are solvents which can remove those paints from plastic models without dissolving the model and sometimes I have soaked airbrush guts in those to make sure all buildup is out. Or to de-clog fellow club members' airbrushes.
Can sometimes simply run clear water through it between colors but after an afternoon's work it is knock down and clean the thing. Which isn't actually as onerous a task as people like me make it sound, but it is a task of import.