Well, GHS in the Handbook cautioned that vent holes should be "equalized" to prevent the "thruster effect."
The sudden puff of gas from the vent port, at least in theory, might be enough to get the tail-end of the upper stage swinging in a lateral direction, just as the upper stage lights, which I would guess could be a recipe for bad things happening after that.
It would probably take a lengthy series of tests to determine if this effect really exists (or to what extent), whether the "thruster effect" is really enough to knock a multistage rocket off course. It obviously can't be a major or consistent effect or everyone would have observed the Centuri single-port rockets always flying way off course.
But, I do know on the gap-staged rockets I have flown, I have always used "equalized" vent-holes and I have never had one take off cockeyed.
Although I do recall way back in my younger rocketry life, I DID have a lower stage that I butted the motors together with several layers of heavy plastic tape, refuse to separate on upper-stage ignition, it hung on (kind of flish-tailing) for about half the upper-stage burn before finally kicking off. The whole kaboodle veered off at about a 60-degree angle before the booster stage kicked off, then the upper stage straightened out and flew about a quarter-mile downrange.
The booster landed 100 feet or so from the pad, with a pretty thick charcoal-smoked effect on its front end.

Which just goes to show that when you use the direct-butting staging method, you want to use one turn (no more) of cellophane or mylar tape (not thick plastic) to butt the motors together. You want that sucker to light and then kick the heck off of there.